USING POWER LOSS DENSITY AND RELATED MEASURES TO QUANTIFY DOSE OF TUMOR TREATING FIELDS (TT FIELDS)

To optimize a location of an electrode array.SOLUTION: The planning of treatment using tumor treating fields (TT Fields) in a portion of a subject's body (e.g., the subject's head) can be improved by obtaining an image of the body portion, and generating, based on the image, a 3D model of...

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Main Authors ARIEL NAVEH, HADAS SARA HERSHKOVICH, LEVI SHAY, NOA URMAN, ZEEV BOMZON
Format Patent
LanguageEnglish
Japanese
Published 19.07.2023
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Summary:To optimize a location of an electrode array.SOLUTION: The planning of treatment using tumor treating fields (TT Fields) in a portion of a subject's body (e.g., the subject's head) can be improved by obtaining an image of the body portion, and generating, based on the image, a 3D model of electrical conductivity. A target volume within the 3D model is identified, and a set of model electrodes is added to the 3D model at given locations. Then, for each voxel in the target volume, the power loss density (PLD) that will be present when TT Fields are eventually applied is determined. The same process is repeated for a plurality of different electrode locations. Finally, the set of electrode locations that yields the best PLD is selected, and a description of those locations is output.SELECTED DRAWING: Figure 2 【課題】電極アレイの位置を最適化する。【解決手段】被験者の身体(たとえば、被験者の頭部)の一部分において腫瘍治療場(TT場)を使用して治療する計画は、身体の一部分の画像を取得すること、および画像に基づいて、導電率の3Dモデルを生成することによって改善することができる。3Dモデル内の標的体積が識別され、モデル電極の組が、所与の場所で3Dモデルに付加される。次いで、標的体積中の各ボクセルについて、TT場が最終的に適用されるときに存在することになる電力損失密度(PLD)が決定される。同じプロセスが、複数の異なる電極の場所について繰り返される。最後に、最良のPLDをもたらす電極のための組の場所が選択され、それらの場所の記述が出力される。【選択図】図2
Bibliography:Application Number: JP20230068769