CHRYSANTHEMUM MORIFOLIUM FLAVONE AGLYCON EXTRACTION METHOD, EXTRACT OBTAINED BY THE SAME, AND ANTI INFLAMMATORY PHARMACEUTICAL COMPOSITION

• Main Authors: LU CHU-HSUN, CHEN WEN-YIN, YANG TSUNG-LIN, CHEN YU-WEN, ANGELA GOH, YAO HSIN-JAN, PAN I-HONG
• Format: Patent
• Language: English; Japanese
• Published: 05.07.2023
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

To provide a method for extracting flavone aglycon such as luteolin and apigenin in Chrysanthemum morifolium.SOLUTION: There is provided a method comprising: (a) a step for immersing a Chrysanthemum morifolium raw material in water or solution, performing an immersion step for 3.5 hours or more, for acquiring an immersed sample; (b) a step for adding an extraction solvent to the immersed sample, performing an extraction step for 5-60 minutes for acquiring the extract. In the Chrysanthemum morifolium, at least one of following portions of the Chrysanthemum morifolium, namely, a whole plant, root, stem, leaf and a flower.SELECTED DRAWING: None 【課題】イエギク中のルテオリン、アピゲニン等のフラボンアグリコンを抽出する方法を提供する。【解決手段】方法は、（ａ）イエギク原料を水または水溶液中に浸し、浸漬工程を３．５時間以上行って浸漬試料を得るステップと、（ｂ）抽出溶媒を浸漬試料中に加え、抽出工程を５～６０分行って抽出液を得るステップとを含む。イエギク原料には、イエギクの下記する部位、つまり全草、根、茎、葉および花のうちの少なくとも１つが含まれる。【選択図】なし