REPORT CREATION METHOD AND REPORT CREATION DEVICE FOR CREATING REPORT REPORTING LEVEL OF PATHOGENESIS OF GENE MUTATIONS

• Main Authors: IZUMI YUKI, WASHIO TAKANORI, NIIRO HAYATO
• Format: Patent
• Language: English; Japanese
• Published: 09.06.2023
• Subjects: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; PHYSICS

To provide appropriate information even if a level of determined pathogenesis may be changed later.SOLUTION: A report creation method creates a report that reports a level of pathogenesis of gene mutation. The report creation method acquires information on the gene mutation detected in gene panel inspection, for a plurality of evaluation items, creates evaluation results on the basis of, a first standard for evaluating the evaluation items and at least the information on the gene mutation, determines the level of the pathogenesis on the basis of, a second standard for determining the level of the pathogenesis and the evaluation results, determines, of the plurality of evaluation items, an unsettled item in which the evaluation result is unsettled and determines whether the level of the pathogenesis is temporary on the basis of, a result of determination of the unsettled item, and according to a result of determination as to whether the level is temporary, creates a report that reports the level of the pathogenesis.SELECTED DRAWING: Figure 3 【課題】判定された病原性の水準が後に変更される可能性がある場合であっても適切な情報を提供すること。【解決手段】レポート生成方法は、遺伝子変異の病原性の水準を報告するレポートを生成する。レポート生成方法は、遺伝子パネル検査で検出された遺伝子変異の情報を取得し、複数の評価項目について、前記各評価項目を評価するための第1基準と、少なくとも前記遺伝子変異の情報と、に基づいて、評価結果を生成し、前記病原性の水準を判定するための第２基準と、前記評価結果と、に基づいて前記病原性の水準を判定し、前記複数の評価項目のうち、前記評価結果が未確定である未確定項目を決定し、前記未確定項目の決定結果に基づいて、前記病原性の水準が暫定的であるか否かを決定し、前記暫定的であるか否かの決定結果に応じて、前記病原性の水準を報告するレポートを生成する。【選択図】図３