METHOD FOR DISTINGUISHING SENILE PIGMENT FRECKLE FROM DNA METHYLATION CHANGES AND RNA EXPRESSION CHANGES

• Main Authors: INOUE DAIGO, ONO RYUSUKE, SHIBATA TAKAKO, NISHIGORI CHIKAKO, TSUTSUI DAIKI, KOIKE SAYA, OBA HIROSHI, KUNISADA MITSURU
• Format: Patent
• Language: English; Japanese
• Published: 25.04.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; TESTING; VINEGAR; WINE

To provide a screening method for a gene involved in blemish formation and a screening method for a substance that inhibits the formation of blemishes or a substance that ameliorates blemishes.SOLUTION: A method comprises: a step of preparing epidermal cells of an isolated pigment-enhanced site; a s...