SYSTEMS AND METHODS FOR SEPARATION OF PLATELETS FROM BLOOD AND RETURN OF MONONUCLEAR CELLS
To provide systems and methods for separating platelets from blood and converting mononuclear cells, and systems and methods for separating platelets from blood.SOLUTION: A blood processing system comprises a centrifugal blood separation device 10 that may be used in combination with a disposable fl...
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Main Author | |
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Format | Patent |
Language | English Japanese |
Published |
21.02.2023
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Subjects | |
Online Access | Get full text |
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Summary: | To provide systems and methods for separating platelets from blood and converting mononuclear cells, and systems and methods for separating platelets from blood.SOLUTION: A blood processing system comprises a centrifugal blood separation device 10 that may be used in combination with a disposable fluid flow circuit. Prior to blood separation, a volume of blood to be processed, a volume of platelets to be collected, and/or a time required to complete a blood draw from a source during a blood separation procedure are determined. Based on that determination, a procedure setpoint is calculated from the completion of the blood draw. Blood is drawn from the source into a separator, in which the blood is separated into a mononuclear cell-containing fraction and a platelet-containing fraction. At least a portion of the platelet-containing fraction is conveyed from the separator, while the volume of the mononuclear cell-containing fraction in the separator increases. The mononuclear cell-containing fraction is conveyed to the source from the separator at the procedure setpoint. The blood draw and separation are then ended.SELECTED DRAWING: Figure 1
【課題】血小板を血液から分離し単核細胞を変換するシステムおよび方法、血小板を血液から分離するためのシステムおよび方法が提供される。【解決手段】血液処理システムは、使い捨て流体流回路と組み合わせて使用され得る遠心血液分離装置10を含む。血液分離に先立って、処理されるべき血液の体積、収集されるべき血小板の体積、および/または、血液分離手順中に供給源からの採血を完了するために必要とされる時間が決定される。この決定に基づいて、手順セットポイントが採血の完了から計算される。血液は供給源から分離器に引き出され、その中で血液は単核細胞含有画分と血小板含有画分とに分離される。血小板含有画分の少なくとも一部は分離器から搬送され、分離器内の単核細胞含有画分の体積が増加する。単核細胞含有画分は手順セットポイントにおいて分離器から供給源に搬送される。その後、採血と分離が終了される。【選択図】図1 |
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Bibliography: | Application Number: JP20220125181 |