METHOD FOR DETECTING CHRONIC PANCREATITIS

• Main Authors: KATO NAOYA, CHIBA TETSUHIRO, NAKAGAWA RYO, KAN MOTOYASU
• Format: Patent
• Language: English; Japanese
• Published: 26.01.2023
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

To provide a method for detecting chronic pancreatitis specifically and non-invasively and a biomarker.SOLUTION: A method for detecting chronic pancreatitis comprising a step of measuring an adrenomedullin content in a blood sample from a subject. The method for detecting chronic pancreatitis further comprises a step of comparing a measured content with a predetermined reference value, where if the measured adrenomedullin content is less than a preset reference value, a subject can be predicted to have chronic pancreatitis. In the method for detecting chronic pancreatitis, a preset reference value is a reference value set based on an ROC analysis.SELECTED DRAWING: None 【課題】慢性膵炎を特異的かつ非侵襲的に検出するための方法及びバイオマーカーの提供。【解決手段】被験対象由来の血液試料中のアドレノメデュリン含有量を測定する工程を含む、慢性膵炎の検出方法。測定した含有量を予め設定した基準値と比較する工程を更に含み、予め設定した基準値が、測定したアドレノメデュリン含有量が該基準値よりも小さい場合、被験対象は慢性膵炎を有すると予測できる基準値である、慢性膵炎の検出方法。予め設定した基準値が、ＲＯＣ解析に基づき設定した基準値である、慢性膵炎の検出方法。【選択図】なし