ANTI-SARS CORONAVIRUS-2 COMPOSITION AND METHOD FOR PRODUCING THE SAME

• Main Authors: WATANABE MASAKI, YASUOKA JUNKO, TAYA ARINORI, SEJIMA YUTA, OBA MASAKI, SUZUKI TAKAHITO, IKEZAWA MASAYA, NISHIKAWA MUNENOBU, WEN RONGDUO, MIZUTANI TETSUYA, SATO YOKO, OKABAYASHI TAMAKI, SAITO AKIRA, FURUKAWA MAKIO, MATSUMOTO MASAKI, YOKOTA TOMOKO, AKATA KEIJI, GOKAN SHUNYA, WATANABE YUJI
• Format: Patent
• Language: English; Japanese
• Published: 09.11.2022
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

To provide a novel anti-SARS coronavirus-2 composition that has antiviral activity against SARS coronavirus-2 and a method for producing the same.SOLUTION: An anti-SARS coronavirus-2 composition contains culture extract of Bacillus subtilis var natto. A method for producing the anti-SARS coronavirus-2 composition includes a liquid culture step for culturing the Bacillus subtilis var natto in a liquid medium and a conditioned medium separation step for separating a conditioned medium of the Bacillus subtilis var natto from the culture medium from the liquid culture step; or includes a solid culture step for adding the Bacillus subtilis var natto to beans for solid culture, and a liquid component separation step for adding an extraction solvent to the culture after the solid culture step and then performing solid-liquid separation to separate the liquid component.SELECTED DRAWING: None 【課題】ＳＡＲＳコロナウイルス－２に対して抗ウイルス活性を有する、新規性の抗ＳＡＲＳコロナウイルス－２用組成物及びその製造方法を提供する。【解決手段】抗ＳＡＲＳコロナウイルス－２用組成物は、納豆菌培養抽出物を含む。前記抗ＳＡＲＳコロナウイルス－２用組成物の製造方法は、前記納豆菌を液体培地で培養する液体培養工程と、前記液体培養工程後の培養液から、前記納豆菌の培養上清を分離する培養上清分離工程と、を含む、又は、前記納豆菌を豆類に添加して固体培養する固体培養工程と、前記固体培養工程後の培養物に抽出溶媒を添加した後、固液分離を行い、液体成分を分離する液体成分分離工程と、を含む。【選択図】なし