INORGANIC POROUS CARRIER AND METHOD FOR PRODUCING NUCLEIC ACID

• Main Authors: HARA TAKASHI, ISHIYAMA TAKESHI, OSHIRO IKUYA
• Format: Patent
• Language: English; Japanese
• Published: 18.11.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DERIVATIVES THEREOF; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; SUGARS; VINEGAR; WINE

To provide an inorganic porous carrier that can improve the purity of a nucleic acid in its production, and a method for producing a nucleic acid with the inorganic porous carrier.SOLUTION: An inorganic porous carrier contains a silyl group represented by formula (i-1) and a silyl group represented by formula (ii-1) or the like and has (iii) a pore size of 20 nm or more and (iv) an external surface tPSA value (Å2) of 56 or more and 83 or less. There is also provided a method for producing a nucleic acid with the inorganic porous carrier.SELECTED DRAWING: None 【課題】核酸の製造において純度等をより高められる無機多孔質担体、およびこれを用いた核酸の製造方法の提供。【解決手段】式（ｉ−１）で表されるシリル基、および式（ｉｉ−１）等で表されるシリル基を有し、（ｉｉｉ）細孔径が２０ｎｍ以上であること、（ｉｖ）外表面ｔＰＳＡ値（Å２）が５６以上、８３以下であること、を特徴とする、無機多孔質担体、およびこれを用いた核酸の製造方法。【選択図】なし