DRUG-DEVICE UNIT CONTAINING QUINAGOLIDE

To provide a pharmaceutical polymeric drug-device unit that improves control of drug release.SOLUTION: A polymeric drug-device unit comprises a polyurethane block copolymer and quinagolide as a pharmaceutically active agent, the polyurethane block copolymer prepared by reacting together a poly(alkyl...

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Main Authors CLAIRE YOUNG, PAUL MCDONALD, MOHAMMAD QADIR, JOAN CARLES ARCE SAEZ, DENIS CARR, GOUHER RABANI, AXEL NICLAS PETRI, ROBERT COCHRANE, JANET HALLIDAY, ALISTAIR ROSS
Format Patent
LanguageEnglish
Japanese
Published 07.10.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide a pharmaceutical polymeric drug-device unit that improves control of drug release.SOLUTION: A polymeric drug-device unit comprises a polyurethane block copolymer and quinagolide as a pharmaceutically active agent, the polyurethane block copolymer prepared by reacting together a poly(alkylene oxide), a difunctional compound, a difunctional isocyanate and, optionally a block copolymer comprising poly(alkylene oxide) blocks.SELECTED DRAWING: Figure 1 【課題】薬物放出の制御を改善する、医薬ポリマー薬物−デバイスユニットを提供する。【解決手段】ポリ（アルキレンオキシド）、二官能性化合物、二官能性イソシアネート、および場合により、ポリ（アルキレンオキシド）ブロックを含むブロックコポリマーを共に反応させることにより得られるポリウレタンブロックコポリマーと、薬学的に活性な剤としてのキナゴリドとを含むポリマー薬物−デバイスユニットとする。【選択図】図１
Bibliography:Application Number: JP20210108386