FUCOSIDASE INHIBITORS

To provide compounds useful as inhibitors of fucosidase enzymes, and methods and compositions for the treatment of tumors or cancers, such as liver disorders and liver tumors, employing the compounds.SOLUTION: The present disclosure relates, in general, to compounds useful as inhibitors of fucosidas...

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Bibliographic Details
Main Authors ZANKEL TODD C, AMANDA ANNE KO, SARA LOUISE ISBELL
Format Patent
LanguageEnglish
Japanese
Published 30.09.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide compounds useful as inhibitors of fucosidase enzymes, and methods and compositions for the treatment of tumors or cancers, such as liver disorders and liver tumors, employing the compounds.SOLUTION: The present disclosure relates, in general, to compounds useful as inhibitors of fucosidase enzymes, and to methods and compositions for the treatment of tumors or cancers, such as liver disorders and liver tumors (e.g., hepatocellular carcinoma), employing a compound disclosed herein.SELECTED DRAWING: Figure 1 【課題】フコシダーゼ酵素の阻害剤として有用な化合物、ならびに化合物を用いた、腫瘍またはがん、例えば、肝臓障害および肝臓腫瘍の処置のための方法および組成物を提供すること【解決手段】 本件の開示は、一般的に、フコシダーゼ酵素の阻害剤として有用である化合物、ならびに、本件の明細書中で開示されているところの化合物を用いた、腫瘍、またはがん、例えば、肝臓障害、および肝臓腫瘍（例えば、肝細胞癌）の処置のための方法、ならびに組成物に関するものである。【選択図】 図１
Bibliography:Application Number: JP20210110088