SYMPATHETIC NERVE ACTIVITY ESTIMATION DEVICE, SYMPATHETIC NERVE ACTIVITY ESTIMATION METHOD, AND PROGRAM

• Main Authors: SOH ZU, OKADA YOSHIYUKI, SAKAGAWA TOSHIKI, FURUI AKIRA, YAMAWAKI SHIGETO, YOSHIZUMI MASAO, SAEKI NOBORU, NAKAMURA TAKAHARU, SASAOKA TAKAFUMI, TSUJI TOSHIO
• Format: Patent
• Language: English; Japanese
• Published: 09.09.2021
• Subjects: DIAGNOSIS; HUMAN NECESSITIES; HYGIENE; IDENTIFICATION; MEDICAL OR VETERINARY SCIENCE; SURGERY

To provide a sympathetic nerve activity estimation device, a sympathetic nerve activity estimation method, and a program that can reduce a physical burden on a subject.SOLUTION: A sympathetic nerve activity estimation device 1 includes a calculation unit 212 for calculating blood vessel rigidity β on the basis of blood pressure and a volume pulse wave, which are biological signals measured non-invasively, and estimating muscle sympathetic nerve activity (MSNA) on the basis of the calculated blood vessel rigidity β. Also, the calculation unit 212 of the sympathetic nerve activity estimation device 1 calculates Total σ as an evaluation index of sympathetic nervous system pressure receptor reflection sensitivity (sBRS).SELECTED DRAWING: Figure 2 【課題】被験者の身体的負担を軽減可能な交感神経活動推定装置、交感神経活動推定方法及びプログラムを提供する。【解決手段】交感神経活動推定装置１は、非侵襲で計測可能な生体信号である血圧及び容積脈波に基づいて血管剛性βを算出し、算出された血管剛性βに基づいて筋交感神経活動（ＭＳＮＡ）を推定する演算部２１２を備える。また、交感神経活動推定装置１の演算部２１２は、交感神経系圧受容体反射感受性（ｓＢＲＳ）の評価指標としてTotal σを算出する。【選択図】図２