PHARMACEUTICAL COMPOSITION FOR EXTERNAL USE

To provide a minoxidil-containing pharmaceutical composition for external use that has good skin compatibility as it is important for a minoxidil-containing pharmaceutical to agree with the surface of scalp and spread well so that minoxidil in the pharmaceutical is efficiently absorbed from the scal...

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Bibliographic Details
Main Authors SAKAMOTO SAORI, TANAKA HIROYUKI
Format Patent
LanguageEnglish
Japanese
Published 30.08.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide a minoxidil-containing pharmaceutical composition for external use that has good skin compatibility as it is important for a minoxidil-containing pharmaceutical to agree with the surface of scalp and spread well so that minoxidil in the pharmaceutical is efficiently absorbed from the scalp.SOLUTION: A pharmaceutical composition for external use contains (a) 5 w/v% or more minoxidil, (b) at least one selected from the group consisting of camphor, benzyl nicotinate, chlorpheniramine maleate, benzalkonium and/or a salt thereof and (c) water. The pharmaceutical composition is suitably used as a solution, lotion or tonic.SELECTED DRAWING: None 【課題】 ミノキシジルを含有する製剤中のミノキシジルが頭皮から効率的に吸収されるためには、ミノキシジルを含有する製剤が頭皮の表面になじみ、広がることが重要である。すなわち、本発明の課題は、肌なじみがよい、ミノキシジル含有外用医薬組成物を提供することである。【解決手段】 本発明は、（ａ）５ｗ／ｖ％以上のミノキシジル、（ｂ）カンフル、ニコチン酸ベンジル、マレイン酸クロルフェニラミン、ベンザルコニウム及び/又はその塩からなる群から選ばれる少なくとも１種、及び（ｃ）水を含有する外用医薬組成物である。本発明は液剤、ローション剤又はトニック剤として好適に用いられるものである。【選択図】なし
Bibliography:Application Number: JP20210008000