CYCLIC AMIDE COMPOUND FOR TREATMENT OF RABIES AND METHOD THEREFOR

• Main Authors: MISHINA TADASHI, NISHIZONO AKIRA, ISHIZAKI TOSHIMASA, YOSHIMORI ATSUSHI, YAMADA KENTARO, KATO AKIRA, MATSUOKA SHIGERU, SHOJI HIROYUKI
• Format: Patent
• Language: English; Japanese
• Published: 26.08.2021
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

To provide a cyclic amide compound that is for the treatment of rabies, and a method therefor.SOLUTION: The present disclosure provides a compound that is useful in the treatment and prevention of rabies. The present disclosure provides: a compound represented by the formula XXIF or the formula XXIB, a solvate or a pharmaceutically acceptable salt thereof; use of the compound, solvate or pharmaceutically acceptable salt thereof for the treatment or prevention of rabies; a pharmaceutical composition comprising the compound, solvate or pharmaceutically acceptable salt thereof; and a method for treating or preventing rabies using the same.SELECTED DRAWING: None 【課題】狂犬病治療のための環状アミド化合物およびその方法の提供。【解決手段】本開示は、狂犬病の治療および予防に有用な化合物を提供する。本開示は、式ＸＸＩＦまたは式ＸＸＩＢ：により表される化合物、溶媒和物またはその薬学的に許容される塩、これらの化合物、溶媒和物またはその薬学的に許容される塩の狂犬病の治療または予防のための用途、これらの化合物、溶媒和物またはその薬学的に許容される塩を含む医薬組成物、およびそれを用いた狂犬病の治療および予防のための方法を提供する。【選択図】なし