USE OF ANTI-FAM19A5 ANTIBODIES FOR TREATING CANCERS

To provide pharmaceutical compositions comprising antagonists (e.g., an antibody or antigen-binding portion thereof) to treat a disease (e.g., cancer) in a subject by promoting a blood vessel normalization.SOLUTION: A pharmaceutical composition comprises an antagonist against a family with sequence...

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Main Authors KIM DONG SIK, KWON SOON-GU, SHIM JUWON, LEE JAE-KEUN, KIM BONGCHEOL, KIM TAE WOO, SEONG JAE YOUNG, CHO EUN BEE, KANG SHIN-HYUK
Format Patent
LanguageEnglish
Japanese
Published 10.06.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide pharmaceutical compositions comprising antagonists (e.g., an antibody or antigen-binding portion thereof) to treat a disease (e.g., cancer) in a subject by promoting a blood vessel normalization.SOLUTION: A pharmaceutical composition comprises an antagonist against a family with sequence similarity 19, member A5 (FAM19A5) protein ("FAM19A5 antagonist").SELECTED DRAWING: None 【課題】血管正常化を促進することにより対象の疾患（例えば、癌）を治療するための、拮抗剤（例えば、抗体又はその抗原結合部分）を含む医薬組成物を提供する。【解決手段】ＦＡＭ１９Ａ５（ｆａｍｉｌｙ ｗｉｔｈ ｓｅｑｕｅｎｃｅ ｓｉｍｉｌａｒｉｔｙ １９、ｍｅｍｂｅｒ Ａ５）タンパク質に対する拮抗剤（ａｎｔａｇｏｎｉｓｔ）（"ＦＡＭ１９Ａ５拮抗剤"）を含む、医薬組成物とする。【選択図】なし
Bibliography:Application Number: JP20210027730