BINDING MOLECULES
To provide binding molecules that can immunospecifically bind to an epitope of 5T4.SOLUTION: There is provided tri-specific binding molecules, which are multichain polypeptide molecules capable of mediating coordinated binding to three epitopes, and which includes CDRL1 having the sequence RASQGISNY...
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Main Authors | , , , , , , , , , |
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Format | Patent |
Language | English Japanese |
Published |
13.05.2021
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Subjects | |
Online Access | Get full text |
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Summary: | To provide binding molecules that can immunospecifically bind to an epitope of 5T4.SOLUTION: There is provided tri-specific binding molecules, which are multichain polypeptide molecules capable of mediating coordinated binding to three epitopes, and which includes CDRL1 having the sequence RASQGISNYLA, CDRL2 having the sequence RANRLQS, and CDRL3 having the sequence LQYDDFPWT.SELECTED DRAWING: Figure 4A
【課題】5T4のエピトープに免疫特異的に結合できる結合分子を提供する。【解決手段】3つのエピトープへの配位結合を仲介できる多重鎖ポリペプチド分子である、三重特異性結合分子であって、配列RASQGISNYLAを有するCDRL1と、配列RANRLQSを有するCDRL2と、及び配列LQYDDFPWTを有するCDRL3とを含む。【選択図】図4A |
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Bibliography: | Application Number: JP20210006240 |