TREATING ORAL LESIONS USING PLACENTAL EXTRACELLULAR MATRIX

To provide compositions and methods useful in treatment of non-dental oral lesions.SOLUTION: Provided herein are compositions comprising extracellular matrix, and methods of treating an individual having an oral lesion, comprising administering to the oral lesion a composition comprising an extracel...

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Bibliographic Details
Main Authors ROBERT J HARIRI, WOLFGANG HOFGARTNER, JODI P GURNEY, MOHIT B BHATIA
Format Patent
LanguageEnglish
Japanese
Published 13.05.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide compositions and methods useful in treatment of non-dental oral lesions.SOLUTION: Provided herein are compositions comprising extracellular matrix, and methods of treating an individual having an oral lesion, comprising administering to the oral lesion a composition comprising an extracellular matrix component. In the compositions and methods, the extracellular matrix is preferably human placental extracellular matrix that has not been chemically modified or contacted with an exogenous protease.SELECTED DRAWING: Figure 1 【課題】非歯科的口腔病変の治療に有用な組成物及び方法を提供する。【解決手段】細胞外マトリクスを含有する組成物、及び細胞外マトリクス成分を含有する組成物を口腔病変へ投与することを含む、口腔病変を有する個体を治療する方法であり、好ましくは細胞外マトリクスが、化学修飾されていないか又は外来性プロテアーゼと接触されていないヒト胎盤の細胞外マトリクスである組成物、及び方法である。【選択図】図１
Bibliography:Application Number: JP20210003902