METHODS FOR TREATING CONDITIONS ASSOCIATED WITH MASP-2 DEPENDENT COMPLEMENT ACTIVATION

To provide methods of inhibiting the effects of MASP-2-dependent complement activation in a human subject suffering from TMA associated with hematopoietic stem cell transplant.SOLUTION: The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory age...

Full description

Saved in:
Bibliographic Details
Main Authors THOMAS DUDLER, GREGORY A DEMOPULOS, HANS-WILHELM SCHWAEBLE
Format Patent
LanguageEnglish
Japanese
Published 22.04.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:To provide methods of inhibiting the effects of MASP-2-dependent complement activation in a human subject suffering from TMA associated with hematopoietic stem cell transplant.SOLUTION: The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation.SELECTED DRAWING: Figure 59 【課題】造血幹細胞移植に関連するTMAに罹患しているヒト対象においてMASP-2依存性補体活性化の効果を阻害する方法を提供する。【解決手段】その必要がある対象に、MASP-2依存性補体活性化を阻害するのに有効な量のMASP-2阻害物質を投与する工程を含む。【選択図】図５９
Bibliography:Application Number: JP20200210933