METHODS FOR PREDICTING CLINICAL OUTCOME OF CANCER

• Main Authors: FRANCOIS COLLIN, BAKER JOFFRE B, LIU MEI-LAN, CRONIN MAUREEN T
• Format: Patent
• Language: English; Japanese
• Published: 15.04.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

To provide methods for determining the prognosis and appropriate treatment for patients diagnosed with cancer, based on the expression levels of one or more biomarkers.SOLUTION: The invention relates to the identification of genes, or sets of genes, able to distinguish breast cancer patients with a good clinical prognosis from breast cancer patients with a bad clinical prognosis. The invention further provides methods for providing a personalized genomics report for a cancer patient. The invention also relates to computer systems and software for data analysis using the prognostic and statistical methods disclosed herein.SELECTED DRAWING: None 【課題】本発明は、１つ又は複数のバイオマーカーの発現レベルに基づき、癌と診断される患者についての予後及び適切な治療を決定する方法を提供する。【解決手段】本発明は、臨床予後が良好な乳癌患者を臨床予後が不良な乳癌患者と区別することが可能な遺伝子、又は遺伝子セットの同定に関する。本発明はさらに、癌患者に個別化されたゲノミクスレポートを提供するための方法を提供する。本発明はまた、本明細書に開示される予後診断的及び統計的方法を用いたデータ分析のためのコンピュータシステム及びソフトウェアにも関する。【選択図】なし