MULTIVALENT AND MULTISPECIFIC DR5-BINDING FUSION PROTEINS

To provide multivalent and multispecific molecules that bind death receptor 5 (DR5).SOLUTION: The disclosure relates to molecules that specifically engage DR5, which is a member of the TNF receptor superfamily (TNFRSF). The disclosure relates to multivalent and multispecific molecules that bind at l...

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Bibliographic Details
Main Authors HUSSAIN ABRAHIM, AMIR S RAZAI, KYLE S JONES, KATELYN M WILLIS, QUINN DEVERAUX, BRENDAN P ECKELMAN, JOHN C TIMMER
Format Patent
LanguageEnglish
Japanese
Published 25.03.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide multivalent and multispecific molecules that bind death receptor 5 (DR5).SOLUTION: The disclosure relates to molecules that specifically engage DR5, which is a member of the TNF receptor superfamily (TNFRSF). The disclosure relates to multivalent and multispecific molecules that bind at least DR5.SELECTED DRAWING: Figure 1 【課題】細胞死受容体５（ＤＲ５）に結合する多価及び多重特異的分子を提供する。【解決手段】ＴＮＦ受容体スーパーファミリー（ＴＮＦＲＳＦ）のメンバーである、ＤＲ５に特異的に関与する分子。少なくともＤＲ５に結合する多価及び多重特異的分子。【選択図】図１
Bibliography:Application Number: JP20200196358