NOVEL FORMULATION

To provide a formulation comprising a DPP-IV inhibitor and metformin in the form of a free-flowing, cohesive tableting powder, capable of being easily granulated or compressed into a tablet.SOLUTION: A tablet is obtained by direct compression of metformin granules and vildagliptin, and desirably at...

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Bibliographic Details
Main Authors KOWALSKI JAMES, VASANTHAVADA MADHAV, TONG WEI-QIN, JOSHI YATINDRA, LAKSHMAN JAY PARTHIBAN, ROYCE ALAN EDWARD
Format Patent
LanguageEnglish
Japanese
Published 21.01.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide a formulation comprising a DPP-IV inhibitor and metformin in the form of a free-flowing, cohesive tableting powder, capable of being easily granulated or compressed into a tablet.SOLUTION: A tablet is obtained by direct compression of metformin granules and vildagliptin, and desirably at least one pharmaceutically acceptable excipient.SELECTED DRAWING: None 【課題】容易に造粒または錠剤に圧縮することが可能な自由流動性である、凝集性錠剤用粉末の形態でのＤＰＰ−ＩＶ阻害剤およびメトホルミンを含む製剤を提供する。【解決手段】メトホルミン顆粒とビルダグリプチン、および所望により少なくとも一つの薬学的に許容される賦形剤との直接圧縮により得られる錠剤。【選択図】なし
Bibliography:Application Number: JP20200151616