FOOT-AND-MOUTH DISEASE VACCINE

To provide compositions for prevention of foot-and-mouth disease (FMD).SOLUTION: An immunogenic composition comprises an antigen component and an adjuvant component, where: a) the adjuvant component comprises an emulsion containing oil, an immunostimulatory oligonucleotide, and at least one of i) a...

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Main Authors JAMES ALAN JACKSON, PAUL JOSEPH DOMINOWSKI, AIDA ELIZABETH RIEDER, CYRIL GERARD GAY, LUIS LEANDRO RODRIGUEZ, JOHN MORGAN HARDHAM, PETER WILLIAM KRUG
Format Patent
LanguageEnglish
Japanese
Published 07.01.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide compositions for prevention of foot-and-mouth disease (FMD).SOLUTION: An immunogenic composition comprises an antigen component and an adjuvant component, where: a) the adjuvant component comprises an emulsion containing oil, an immunostimulatory oligonucleotide, and at least one of i) a polycationic polymer and ii) a source of aluminum; and b) the antigen component comprises 0.5-10 μg of an FMD virus composition per dose.SELECTED DRAWING: Figure 1 【課題】口蹄疫（ＦＭＤ）の予防のための組成物の提供。【解決手段】抗原成分及びアジュバント成分を含む免疫原性組成物であって、ａ）前記アジュバント成分が、油、免疫刺激性オリゴヌクレオチド、及びｉ）ポリカチオン性高分子、若しくはｉｉ）アルミニウム源、のうちの少なくとも１つ、を含有するエマルションを含み、ｂ）前記抗原成分が、０．５〜１０μｇ／用量のＦＭＤウイルス組成物を含む、前記免疫原性組成物。【選択図】図１
Bibliography:Application Number: JP20200157185