ANTI-CD79b ANTIBODIES AND METHODS OF USE

• Main Authors: POLSON ANDREW, CHEN YVONNE MAN-YEE, ALLEN J EBENS JR, MARK S DENNIS, LIPING L SUN
• Format: Patent
• Language: English; Japanese
• Published: 15.10.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

To provide anti-CD79b antibodies and methods of using the same.SOLUTION: The invention provides: isolated anti-CD79b antibodies comprising a CD79b binding domain comprising six hypervariable regions (HVRs); pharmaceutical compositions comprising the antibodies; and the anti-CD79b antibodies for use in treating or delaying the progression of a B cell proliferative disorder or autoimmune disorder in a subject in need thereof.SELECTED DRAWING: None 【課題】抗ＣＤ７９ｂ抗体及びその使用方法を提供する。【解決手段】単離された抗ＣＤ７９ｂ抗体であって、特定の６つの超可変領域（ＨＶＲ）を含む、ＣＤ７９ｂ結合ドメインを含む、前記抗体。前記抗体を含む、薬学的組成物。Ｂ細胞増殖性障害または自己免疫性障害の進行の治療または遅延を必要とする対象において、それに使用するための前記抗ＣＤ７９ｂ抗体。【選択図】なし