PREVENTING OR AMELIORATING AGENT FOR AGE-RELATED COGNITIVE DYSFUNCTION, ENHANCER FOR NEUROTROPHIN 3, PREVENTING OR AMELIORATING AGENT FOR AGE-RELATED DECLINE IN EAGERNESS, AND METHOD FOR PRODUCING THEM

• Main Authors: YOSHIDA KATSUSHI, NOMURA SACHIKO, MONOBE MANAMI, NESUMI ATSUSHI, YAMASHITA NAGAYA
• Format: Patent
• Language: English; Japanese
• Published: 24.09.2020
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

To provide a preventing or ameliorating agent for age-related cognitive dysfunction and to provide an enhancer for neurotrophin 3.SOLUTION: The preventing or ameliorating agent for age-related cognitive dysfunction includes tea leaf or a tea leaf extract being an extract extracted from the tea leaf. In the preventing or ameliorating agent, the tea leaf and the tea leaf extract include non-gallate-type catechin and theogallin and have a ratio of a molar concentration (μmol/L) of theogallin to a molar concentration (μmol/L) of non-gallate-type catechin of 0.3 or more. The enhancer for neurotrophin 3 includes tea leaf and a tea leaf extract being an extract extracted from the tea leaf. In the enhancer for neurotrophin 3, the tea leaf and the tea leaf extract include non-gallate-type catechin and theogallin and have a ratio of a molar concentration (μmol/L) of theogallin to a molar concentration (μmol/L) of non-gallate-type catechin of 0.3 or more.SELECTED DRAWING: Figure 3 【課題】加齢に伴う認知機能障害の予防又は改善剤、及び、ニューロトロフィン３の増強剤を提供すること。【解決手段】茶葉又は該茶葉の抽出物である茶葉抽出物を含む、加齢に伴う認知機能障害の予防又は改善剤であって、前記茶葉及び前記茶葉抽出物は、非ガレート型カテキン及びテオガリンを含み、非ガレート型カテキンのモル濃度（μｍｏｌ／Ｌ）に対するテオガリンのモル濃度（μｍｏｌ／Ｌ）の割合が、０．３以上である、加齢に伴う認知機能障害の予防又は改善剤、及び、茶葉又は該茶葉の抽出物である茶葉抽出物を含む、ニューロトロフィン３の増強剤であって、前記茶葉及び前記茶葉抽出物は、非ガレート型カテキン及びテオガリンを含み、非ガレート型カテキンのモル濃度（μｍｏｌ／Ｌ）に対するテオガリンのモル濃度（μｍｏｌ／Ｌ）の割合が、０．３以上である、ニューロトロフィン３の増強剤。【選択図】図３