POLYPEPTIDES FOR HYDROLYZING ZEARALENONE AND/OR ZEARALENONE DERIVATIVES, ISOLATED POLYNUCLEOTIDES THEREFOR AND POLYPEPTIDE-CONTAINING ADDITIVES, USE OF THE POLYPEPTIDES AND METHODS

• Main Authors: GERD SCHATZMAYR, SEBASTIAN FRUHAUF, MICHAELA THAMHESL, DIETER MOLL, EVA MARIA BINDER, MARTIN PFEFFER
• Format: Patent
• Language: English; Japanese
• Published: 27.08.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

To provide methods for hydrolyzing a mycotoxin produced by a variety of fusarium fungi called zearalenone (ZEN), or at least one zearalenone derivative, and methods for reducing fusarium contamination of foods and animal feed products using the same.SOLUTION: Disclosed is method for hydrolyzing zearalenone or at least one zearalenone derivative using a polypeptide having a specific amino acid sequence, or a variant thereof having an amino acid sequence at least 92% identical to the specific amino acid sequence.SELECTED DRAWING: Figure 3A 【課題】様々なフザリウム菌により生成されるマイコトキシン類のゼアラレノン（ＺＥＮ）又は少なくとも１つのゼアラレノン誘導体を加水分解する方法、それを用いた食品及び動物飼料製品のＺＥＮ汚染を減少させるための方法の提供。【解決手段】特定の配列で表されるアミノ酸配列を有するポリペプチド、又は特定の配列で表されるアミノ酸配列と少なくとも９２％の配列同一性を有するアミノ酸配列を有するその変異体により、ゼアラレノン又は少なくとも１つのゼアラレノン誘導体を加水分解する方法。【選択図】図３Ａ