INFLUENZA VACCINE COMPOSITION FOR INTRADERMAL ADMINISTRATION USE

• Main Authors: MOTOKAWA KENJI, KARAUSHI GEN, ANNAKA RYOSUKE, ENOMOTO TADASHI, TAKESHITA FUMIHIKO, TAKAHAMA AKIKO, HAGIWARA YUKARI
• Format: Patent
• Language: English; Japanese
• Published: 13.08.2020
• Subjects: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

To provide an influenza vaccine preparation for intradermal administration use, which ensures the delivery of an influenza vaccine antigen to an upper layer part of human skin to highly increase an HI antibody titer in an earlier stage in the prevention of influenza infection, and which is highly safe.SOLUTION: An influenza vaccine preparation using an intradermal administration device designed to ensure the delivery of a vaccine preparation to an upper layer part of skin with a tip of a needle tube, and a method for preventing influenza using the preparation.SELECTED DRAWING: Figure 1 【課題】インフルエンザ感染予防において、インフルエンザワクチン抗原をヒト皮膚上層部に確実に送達することにより、早期かつ高いＨＩ抗体価上昇を可能とし、かつ安全性の高い皮内投与インフルエンザワクチン製剤を提供すること。【解決手段】針管の針先を皮膚上層部に確実にワクチン製剤を投与できるよう設計された皮内投与用デバイスを用いたインフルエンザワクチン製剤、及び該製剤を用いるインフルエンザの予防方法。【選択図】図１