PERIPHERAL CIRCULATING TUMOR CELL AND RARE CELL CONCENTRATION DEVICE

• Main Authors: SHIBA KIYOTAKA, KINUTA KIYOSHIZU, ICHINOZAWA YOSHIYUKI, KOBAYASHI MASASHI, MATSUZAKA SATOSHI
• Format: Patent
• Language: English; Japanese
• Published: 27.07.2020
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

To collect a peripheral circulating tumor cell (CTC), or a rare cell in a biological fluid by sorting them to the cell in which a cluster is formed, and the cell in which the cluster is not formed.SOLUTION: A cell in which a cluster is formed, and a cell which singly exists are sorted and collected by arranging a device in which two collection units having filters different in hole diameters are connected to each other.SELECTED DRAWING: Figure 1 【課題】体液中の末梢循環腫瘍細胞（ＣＴＣ）、又は希少細胞をクラスター形成しているものとしていないものとを分離して捕捉することを課題とする。【解決手段】それぞれ異なる孔径のフィルターが配置されている２つの捕捉ユニットが連結されたデバイスとすることによって、クラスター形成している細胞と、単独で存在する細胞を分別して捕捉することができる。【選択図】図１