ANEMIA TREATMENT APPLICATIONS OF TNF ANTAGONIST AND IL-1 INHIBITOR COMBINED PARTLY WITH RECOMBINANT ERYTHROPOIETIN

To provide a method of treating a blood disorder in a mammal by raising the hematocrit.SOLUTION: The method comprises administering, to the mammal, an interleukin-1 inhibitor, which is a chimeric protein comprising an interleukin-1 receptor antagonist and an Fc domain, and an erythropoietin receptor...

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Bibliographic Details
Main Authors COCCIA MARCO A, NEWMARK RICHARD, KAY JONATHAN, MCCABE DOROTHY
Format Patent
LanguageEnglish
Japanese
Published 16.01.2020
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide a method of treating a blood disorder in a mammal by raising the hematocrit.SOLUTION: The method comprises administering, to the mammal, an interleukin-1 inhibitor, which is a chimeric protein comprising an interleukin-1 receptor antagonist and an Fc domain, and an erythropoietin receptor agonist such as epoetin.SELECTED DRAWING: None 【課題】ヘマトクリットを上昇させ、哺乳動物における血液障害を治療する方法の提供。【解決手段】インターロイキン１受容体アンタゴニストとＦｃドメインとを含むキメラタンパク質であるインターロイキン１インヒビターとエポエチン等のエリスロポエチン受容体アゴニストを該哺乳動物に投与することを含んでなる方法。【選択図】なし
Bibliography:Application Number: JP20190166904