THERAPY WITH CELLS FROM HUMAN PLACENTA AND HEMATOPOIETIC CELLS

To provide methods for reducing the severity or duration of graft versus host disease, and for treating or ameliorating symptoms of metabolic disorders and hematologic diseases, such as hematologic malignancies.SOLUTION: A method of transplanting human umbilical cord blood (UCB) cells to a subject c...

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Bibliographic Details
Main Authors ROBERT J HARIRI, ZHANG XIAOKUI, JODI P GURNEY, STACY HERB
Format Patent
LanguageEnglish
Japanese
Published 07.11.2019
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide methods for reducing the severity or duration of graft versus host disease, and for treating or ameliorating symptoms of metabolic disorders and hematologic diseases, such as hematologic malignancies.SOLUTION: A method of transplanting human umbilical cord blood (UCB) cells to a subject comprises administering UCB cells in combination with a population of mononuclear cells from human placental perfusate, where the UCB cells are not related to the subject.SELECTED DRAWING: None 【課題】移植片対宿主病の重症度または持続期間を減少させ、代謝異常や血液悪性腫瘍などの血液学的疾患の症状を治療または寛解するための方法の提供。【解決手段】ヒト臍帯血（ＵＣＢ）細胞を対象に移植する方法であって、ヒト胎盤灌流液由来の単核球の集団と組み合わせてＵＣＢ細胞を投与することを含み、前記ＵＣＢ細胞は、前記対象と非血縁である、方法。【選択図】なし
Bibliography:Application Number: JP20190112450