RNA INTERFERENCE AGENTS FOR GST-π GENE MODULATION

• Main Authors: MOHAMMAD AHMADIAN, JENS HARBORTH, TAKAHASHI HIROICHI, ZHANG JUN, AJINOMI KENJIRO, TERADA ERIKA, YING WENBIN
• Format: Patent
• Language: English; Japanese
• Published: 31.10.2019
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

To provide compounds for modulating human GST-π using RNA interference.SOLUTION: Disclosed herein is a nucleic acid molecule that inhibits expression of GST-π comprising a sense strand and an antisense strand and forms a double stranded region, where the antisense strand comprises a nucleotide seque...