STABLE NOVEL ERYTHROCYTE PRODUCTION STIMULATION PROTEIN PREPARATION

To provide a liquid composition containing darbepoetin alfa that contains a stabilizer for dealing with various kinds of undesired deteriorations, is easy to handle, and can be stored for a long time.SOLUTION: A liquid composition contains darbepoetin alfa and at least arginine and other amino acids...

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Bibliographic Details
Main Authors UECHI KAZUHIRO, MAKITA YOSHIMICHI, MIYAJI ATSUSHI, HASHIMOTO HIROYUKI
Format Patent
LanguageEnglish
Japanese
Published 05.09.2019
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide a liquid composition containing darbepoetin alfa that contains a stabilizer for dealing with various kinds of undesired deteriorations, is easy to handle, and can be stored for a long time.SOLUTION: A liquid composition contains darbepoetin alfa and at least arginine and other amino acids as a stabilizer. The other amino acids include preferably methionine.SELECTED DRAWING: None 【課題】様々な望ましくない変質に対応するための安定化剤を含有し、取扱いが簡便で長期間保存可能なダルベポエチンアルファを含有する液体組成物を提供することを課題とする。【解決手段】ダルベポエチンアルファ及び安定化剤として少なくともアルギニンとその他のアミノ酸とを含むことを特徴とする液体組成物。その他のアミノ酸は特にメチオニンが好ましい。【選択図】 なし
Bibliography:Application Number: JP20180032813