COMPOUND FOR MODIFYING CYTOPLASM GENOME AND USE THEREOF

To provide a compound useful for modifying a cytoplasm genome such as plastid and use thereof.SOLUTION: An agent for constituting a cytoplasm genome of eucaryote contains one of the following (1) and (2): (1) a fusion polypeptide including a polypeptide having a DNA double-strand breaking activity a...

Full description

Saved in:
Bibliographic Details
Main Authors TANAKA HIDENORI, SUGIMOTO HIROKI, MURAMOTO NOBUHIKO, TANAKA TOMOKO, YOGO RITSUKO
Format Patent
LanguageEnglish
Japanese
Published 11.07.2019
Subjects
Online AccessGet full text

Cover

Loading…
More Information
Summary:To provide a compound useful for modifying a cytoplasm genome such as plastid and use thereof.SOLUTION: An agent for constituting a cytoplasm genome of eucaryote contains one of the following (1) and (2): (1) a fusion polypeptide including a polypeptide having a DNA double-strand breaking activity and a transfer element to a cell organelle having a cytoplasm genome and (2) a polynucleotide encoding the fusion polypeptide.SELECTED DRAWING: None 【課題】プラスチドなどの細胞質ゲノムの改変に有用な化合物及びその利用を提供する。【解決手段】真核生物の細胞質ゲノムを編成する剤として、以下の(1)及び(2)のいずれかを含有するものとする。(1)DNA二本鎖切断活性を有するポリペプチドと、細胞質ゲノムを有する細胞小器官に対する転移要素と、を備える融合ポリペプチド(2)前記融合ポリペプチドをコードするポリヌクレオチド【選択図】なし
Bibliography:Application Number: JP20180119457