DEVICE AND METHOD FOR DETECTING MOLECULES

• Main Authors: MIYAMOTO HIROHISA, OKI MITSUHIRO, YAMADA HIROSHI, ATSUTA MASAKI, MATSUNE YASUSHI, YOSHIMURA REIKO, NAKAMURA HIROKO
• Format: Patent
• Language: English; Japanese
• Published: 11.04.2019
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

To enable selective and high-sensitivity detection of target molecules.SOLUTION: A molecule detection device comprises: a measurement chamber; a detector comprising a light source that is provided in the measurement chamber to irradiate light and at least one sensor unit provided in the measurement chamber and configured to capture target molecules, the detector being configured to generate first detection data corresponding to the number of captured target molecules per unit time under a first light irradiation condition and second detection data corresponding to the number of captured target molecules per unit time under a second light irradiation condition; and a discriminator configured to discriminate the target molecules using the first detection data and the second detection data.SELECTED DRAWING: Figure 1 【課題】検出対象分子を選択的にかつ高感度に検出する。【解決手段】分子検出装置は、測定室と、測定室に設けられ、光を照射する光源と、測定室に設けられ且つ検出対象分子を捕捉する少なくとも一つのセンサユニットを有し、光の第１の照射条件下における単位時間あたりの検出対象分子の捕捉数に対応する第１の検出データと、光の第２の照射条件下における単位時間あたりの検出対象分子の捕捉数に対応する第２の検出データと、を生成する検出器と、第１の検出データおよび第２の検出データを用いて検出対象分子を識別する識別器と、を具備する。【選択図】図１