AZASPIRO[4.5] DECANE DERIVATIVES AND USE THEREOF

To provide azaspiro[4.5]decane derivatives, and pharmaceutically acceptable salts, solvates, hydrates, N-oxides, and diastereomers thereof.SOLUTION: There is provided use of pharmaceutically acceptable salts, solvates, hydrates, N-oxides, and diastereomers of azaspiro[4.5]decane derivatives, to trea...

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Bibliographic Details
Main Authors PARK JAE HYUN, MARK A YOUNGMAN, TAFESSE LAYKEA
Format Patent
LanguageEnglish
Japanese
Published 28.02.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide azaspiro[4.5]decane derivatives, and pharmaceutically acceptable salts, solvates, hydrates, N-oxides, and diastereomers thereof.SOLUTION: There is provided use of pharmaceutically acceptable salts, solvates, hydrates, N-oxides, and diastereomers of azaspiro[4.5]decane derivatives, to treat pain. Compounds of the invention are useful for treating a disorder responsive to blockade of one or more sodium channels.SELECTED DRAWING: None 【課題】アザスピロ[４．５]デカン誘導体、並びに、その薬学的に許容可能な塩、溶媒和物、水和物、Ｎ−オキシド、及びジアステレオマーの提供。【解決手段】本化合物は、疼痛を治療するために、アザスピロ[４．５]デカン誘導体の薬学的に許容可能な塩、溶媒和物、水和物、Ｎ−オキシド、及びジアステレオマーの使用を提供する。本化合物は、１つまたは複数のナトリウムチャネルの遮断に応答する障害を治療するのに有用である。【選択図】なし
Bibliography:Application Number: JP20180194973