INHIBITORS OF BENZO[a]PYRENE-INDUCED DNA DAMAGE

• Main Authors: NAKAJIMA SOICHI, ODA YOSHIMI
• Format: Patent
• Language: English; Japanese
• Published: 21.02.2019
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

To provide novel inhibitors of benzo[a]pyrene-induced DNA damage with superior inhibition effect and high safety, and compositions comprising the same.SOLUTION: The invention relates to an inhibitor of DNA damage induced by benzo[a]pyrene comprising an extract of Bacopa monniera or monieroside A that is contained in the extract as an effective ingredient, as well as compositions comprising the inhibitor of benzo[a]pyrene-induced DNA damage.SELECTED DRAWING: None 【課題】ベンゾ[a]ピレンによるDNA損傷の阻害効果に優れ、かつ、安全性も高い、新規なベンゾ[a]ピレン誘発DNA損傷の阻害剤及びそれを含有する組成物を提供すること。【解決手段】オトメアゼナの抽出物を有効成分として含有してなる、ベンゾ[a]ピレン誘発DNA損傷の阻害剤、あるいは、オトメアゼナ抽出物に含まれる成分のモニエロサイドＡを有効成分として含有してなる、ベンゾ[a]ピレン誘発DNA損傷の阻害剤、ならびに、前記ベンゾ[a]ピレン誘発DNA損傷の阻害剤を含有してなる組成物。【選択図】なし