COMPOSITIONS COMPRISING AN EXTRACT OF PIPER LONGUM L. FOR PREVENTING, TREATING AND IMPROVING VOIDING DYSFUNCTION

• Main Authors: KIM KWANG-HYUN, JEON CHAN-SEOK, PARK DA-AE, LEE HYUN-YONG, LEE SANG-HO, CHANG YOON-YOUNG
• Format: Patent
• Language: English; Japanese
• Published: 31.01.2019
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

To provide a pharmaceutical composition comprising an extract of Piper Longum L. as an effective ingredient for preventing or treating voiding dysfunction, as well as health functional food comprising an extract of Piper Longum L. for preventing or improving voiding dysfunction.SOLUTION: The invention relates to a pharmaceutical composition for preventing or treating voiding dysfunction and a health functional food for preventing or improving voiding dysfunction, both comprising an extract of Piper Longum L. as an active ingredient. The extract of Piper Longum L. according to the invention is a natural extract and not only harmless to the human body, but also has outstanding effects of preventing, treating and improving voiding dysfunction by being involved in various mechanisms related to voiding dysfunction simultaneously so that it may increase a micturition interval, decrease a micturition pressure, increase a bladder capacity, inhibit detrusor contraction and induce relaxation of detrusor.SELECTED DRAWING: Figure 5 【課題】インドナガコショウ（Ｐｉｐｅｒ Ｌｏｎｇｕｍ Ｌ．）抽出物を有効成分として含む排尿障害の予防又は治療用の薬学的組成物の提供。インドナガコショウ（Ｐｉｐｅｒ Ｌｏｎｇｕｍ Ｌ．）抽出物を有効成分として含む排尿障害の予防又は改善用の健康機能食品の提供。【解決手段】本発明は、インドナガコショウ（Ｐｉｐｅｒ Ｌｏｎｇｕｍ Ｌ．）抽出物を有効成分として含む排尿障害の予防又は治療用の薬学的組成物及び排尿障害の予防又は改善用の健康機能食品に関する。本発明のインドナガコショウ抽出物は、天然抽出物であり、人体に無害であるだけではなく、排尿障害に関与する様々な機序に同時に関与することにより排尿間隔を増加させ、排尿圧を減少させ、膀胱の容積を増加させ、排尿筋の収縮を抑制し、排尿筋の弛緩を誘導することができる。様々な排尿障害を予防、治療又は改善する効果に優れている。【選択図】図５