HYDROGEL CAPABLE OF CARRYING HETEROCYCLIC COMPOUND

• Main Authors: SATO TAKAO, YAMAZAKI YOSHIKO, KUBOTA YUKIKO
• Format: Patent
• Language: English; Japanese
• Published: 27.12.2018
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; GENERAL PROCESSES OF COMPOUNDING; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS; WORKING-UP

To provide a hydrogel useful as a carrier of agents difficult to carry by the conventional art, such as pyridine derivatives, pyrimidine derivatives, pyridazine derivatives and pyrazine derivatives.SOLUTION: An embodiment of the present invention is a hydrogel containing, as its components, a monocyclic or polycyclic, 3-12 membered heterocyclic monomer that has at least one nitrogen atom in rings, where atoms adjacent to the nitrogen atoms in the rings have amino groups, and a hydrophilic monomer.SELECTED DRAWING: Figure 1 【課題】本発明の目的は、従来技術によって担持することが困難である薬剤、特に、ピリジン誘導体、ピリミジン誘導体、ピリダジン誘導体やピラジン誘導体の担持体として有用なハイドロゲルを提供することにある。【解決手段】上記目的は、環内に少なくとも１つの窒素原子を有し、かつ、環内の該窒素原子に隣り合う原子がアミノ基を有する、単環式又は多環式の３〜１２員複素環式モノマーと、親水性モノマーとを構成成分として含むハイドロゲルなどにより解決される。【選択図】図１