METHODS FOR TREATING NEOPLASIA
PROBLEM TO BE SOLVED: To provide methods for treating cancer.SOLUTION: Disclosed herein is a method for ameliorating cancer in a subject comprising administering an effective amount of IL-2 fusion protein and one or more therapeutic agents to a subject in need thereof thereby ameliorating cancer. In...
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Format | Patent |
Language | English Japanese |
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08.11.2018
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Abstract | PROBLEM TO BE SOLVED: To provide methods for treating cancer.SOLUTION: Disclosed herein is a method for ameliorating cancer in a subject comprising administering an effective amount of IL-2 fusion protein and one or more therapeutic agents to a subject in need thereof thereby ameliorating cancer. In one embodiment, the IL-2 fusion protein does not specifically target or bind to the cancer. In another embodiment, the IL-2 fusion protein comprises a T cell receptor (TCR) domain. In yet another embodiment, the T cell receptor domain is a single chain T cell receptor.SELECTED DRAWING: Figure 1
【課題】癌を治療する方法の提供。【解決手段】有効量のIL−2融合タンパク質および1つまたは複数の治療薬を、それを必要とする被験者に投与し、これにより癌を改善することを含む、被験者において癌を改善する方法。前記IL−2融合タンパク質が癌を特異的に標的としないまたは癌に結合しない、前記方法。前記IL−2融合タンパク質がT細胞受容体(TCR)ドメインを含む、前記方法。前記T細胞受容体ドメインが一本鎖T細胞受容体である、前記方法。【選択図】図1 |
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AbstractList | PROBLEM TO BE SOLVED: To provide methods for treating cancer.SOLUTION: Disclosed herein is a method for ameliorating cancer in a subject comprising administering an effective amount of IL-2 fusion protein and one or more therapeutic agents to a subject in need thereof thereby ameliorating cancer. In one embodiment, the IL-2 fusion protein does not specifically target or bind to the cancer. In another embodiment, the IL-2 fusion protein comprises a T cell receptor (TCR) domain. In yet another embodiment, the T cell receptor domain is a single chain T cell receptor.SELECTED DRAWING: Figure 1
【課題】癌を治療する方法の提供。【解決手段】有効量のIL−2融合タンパク質および1つまたは複数の治療薬を、それを必要とする被験者に投与し、これにより癌を改善することを含む、被験者において癌を改善する方法。前記IL−2融合タンパク質が癌を特異的に標的としないまたは癌に結合しない、前記方法。前記IL−2融合タンパク質がT細胞受容体(TCR)ドメインを含む、前記方法。前記T細胞受容体ドメインが一本鎖T細胞受容体である、前記方法。【選択図】図1 |
Author | WONG HING C WEN JINGHAI XU WENXIN PETER RHODE |
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Snippet | PROBLEM TO BE SOLVED: To provide methods for treating cancer.SOLUTION: Disclosed herein is a method for ameliorating cancer in a subject comprising... |
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Title | METHODS FOR TREATING NEOPLASIA |
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