3-(ARYL OR HETEROARYL) METHYLENEINDOLIN-2-ONE DERIVATIVES AS INHIBITORS OF CANCER STEM CELL PATHWAY KINASES FOR TREATMENT OF CANCER

To provide inhibitors of cancer stem cells.SOLUTION: The invention provides compounds of the formula as inhibitors of cancer stem cells as well as cancer stem cell pathway kinases and other related kinases.SELECTED DRAWING: None 【課題】がん幹細胞の阻害剤の提供。【解決手段】がん幹細胞ならびにがん幹細胞経路キナーゼおよび他の関連キナーゼの阻害剤としての式の化合物。【選択...

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Main Authors LIU JI-FENG, AMANDA GIBEAU, HARRY ROGOFF, TOJO SHINGO, LEE WAI, KANAI TOSHIO, CHIANG J LI, TAKANASHI YOSUKE, KUBOTA KATSUMI, TSUBOI KATSUNORI, KODAMA TOMOHIRO
Format Patent
LanguageEnglish
Japanese
Published 01.11.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide inhibitors of cancer stem cells.SOLUTION: The invention provides compounds of the formula as inhibitors of cancer stem cells as well as cancer stem cell pathway kinases and other related kinases.SELECTED DRAWING: None 【課題】がん幹細胞の阻害剤の提供。【解決手段】がん幹細胞ならびにがん幹細胞経路キナーゼおよび他の関連キナーゼの阻害剤としての式の化合物。【選択図】なし
Bibliography:Application Number: JP20180129002