CRYSTALLINE FORMS OF ANDROGEN RECEPTOR MODULATOR

• Main Authors: OUATHEK OUERFELLI, NICHOLAS D SMITH, MARK R HERBERT, ANNA DILHAS
• Format: Patent
• Language: English; Japanese
• Published: 13.09.2018
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

PROBLEM TO BE SOLVED: To provide a novel androgen receptor modulator.SOLUTION: This invention provides amorphous and crystalline forms of the androgen receptor modulator, 4-[7-(6-cyano-5-trifluoromethylpyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methylbenzamide.SELECTED DRAWING: None 【課題】新規アンドロゲン受容体変調剤の提供。【解決手段】アンドロゲン受容体変調剤４−［７−（６−シアノ−５−トリフルオロメチルピリジン−３−イル）−８−オキソ−６−チオキソ−５，７−ジアザスピロ［３．４］オクト−５−イル］−２−フルオロ−Ｎ−メチルベンズアミドの非晶質形態及び結晶質形態。【選択図】なし