OREXIN RECEPTOR ANTAGONISTS

PROBLEM TO BE SOLVED: To provide chemically related compounds as antagonists of orexin receptors or for treatment of orexin system dysfunction.SOLUTION: The disclosure relates to compounds of the formula in the figure, where Y, Y, Yand Yare each independently a carbon or nitrogen atom, W is substitu...

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Bibliographic Details
Main Authors BENJAMIN GERALD TEHAN, SARAH JOANNE AVES, CHRISTOPHER JOHN ANDREW, SUKHBINDER SINGH KLAIR, MILES STUART CONGREVE
Format Patent
LanguageEnglish
Japanese
Published 30.08.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide chemically related compounds as antagonists of orexin receptors or for treatment of orexin system dysfunction.SOLUTION: The disclosure relates to compounds of the formula in the figure, where Y, Y, Yand Yare each independently a carbon or nitrogen atom, W is substituted aryl or the like, and X is optionally substituted aryl or the like.SELECTED DRAWING: None 【課題】オレキシン受容体のアンタゴニストとしてのまたはオレキシン系機能障害の治療のための化学的に関連する化合物の提供。【解決手段】下式の化合物。［Ｙ１、Ｙ２、Ｙ３およびＹ４：独立して炭素原子または窒素原子、Ｗ：置換されたアリール等、Ｘ：置換されていてもよいアリール等］【選択図】なし
Bibliography:Application Number: JP20180072560