ISOINDOLINONE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE
PROBLEM TO BE SOLVED: To provide compounds useful as inhibitors of PI3K, particularly of PI3Kγ.SOLUTION: The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising the compounds and m...
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Main Authors | , , , , , , , , , , , , , , , , |
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Format | Patent |
Language | English Japanese |
Published |
23.08.2018
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Subjects | |
Online Access | Get full text |
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Summary: | PROBLEM TO BE SOLVED: To provide compounds useful as inhibitors of PI3K, particularly of PI3Kγ.SOLUTION: The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising the compounds and methods of using the compositions in the treatment of various disease, conditions or disorders. The compositions may comprise a pharmaceutically acceptable carrier, adjuvant or vehicle, and may further comprise a therapeutic agent such as an agent for treating multiple sclerosis, an anti-inflammatory agent, an immunomodulatory agent or an immunosuppressive agent.SELECTED DRAWING: None
【課題】PI3K、特に、PI3Kγのインヒビターとして有用な化合物を提供すること。【解決手段】本発明は、PI3K、特に、PI3Kγのインヒビターとして有用な化合物に関する。本発明はまた、前記化合物を含む薬学的に許容され得る組成物、および様々な疾患、状態または障害の処置においてその組成物を使用する方法も提供する。本発明の組成物は、薬学的に許容され得るキャリア、佐剤またはビヒクルを含んでもよく、また、多発性硬化症を処置するための薬剤、抗炎症剤、免疫調節剤または免疫抑制剤などの治療薬をさらに含んでもよい。【選択図】なし |
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Bibliography: | Application Number: JP20180079069 |