PARTICLE-CONTAINING COMPOSITION, IMMUNOASSAY REAGENT, IMMUNOASSAY METHOD AND PARTICLE STORAGE METHOD

• Main Author: MIYAMORI MASAMITSU
• Format: Patent
• Language: English; Japanese
• Published: 09.08.2018
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

PROBLEM TO BE SOLVED: To provide a particle-containing composition that improves the stability of an NS3 region of an HCV antigen immobilized on the particle surface, and allows continuously stable measurement, and provide an immunoassay reagent, an immunoassay method and a particle storage method.SOLUTION: A particle-containing composition contains a particle (A) having an NS3 region of an HCV antigen immobilized on its surface, gelatin (B) and water and has a pH of 7-9. Preferably, the particle-containing composition further contains saccharides (C), and preferably, a weight ratio of gelatin (B) to saccharides (C) [(B)/(C)] is 0.025-1.6.SELECTED DRAWING: None 【課題】粒子表面に固定化したＨＣＶ抗原のＮＳ３領域の安定性を高め、継続的に安定した測定が可能な粒子含有組成物、免疫測定用試薬、免疫測定方法及び粒子の保存方法を提供する。【解決手段】表面にＨＣＶ抗原のＮＳ３領域を固定化した粒子（Ａ）、ゼラチン（Ｂ）及び水を含有し、ｐＨが７〜９である粒子含有組成物。前記粒子含有組成物は更に糖類（Ｃ）を含有することが好ましく、糖類（Ｃ）に対するゼラチン（Ｂ）の重量比率［（Ｂ）／（Ｃ）］は０．０２５〜１．６であることが好ましい。【選択図】なし