SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF CARDIOVASCULAR DISORDERS

• Main Authors: CHRISTOPH GERDES, HENRIK TELLER, ADRIAN TERSTEEGEN, ANJA BUCHMUELLER, MARTINA SCHAEFER, ELOISA JIMENEZ NUNEZ, TOM KINZEL, KARL-HEINZ SCHLEMMER, JUERGEN KLAR, MARTINA VICTORIA SCHMIDT, JULIA STRASSBURGER, STEFAN HEITMEIER, SUSANNE ROEHRIG, ALEXANDER HILLISCH, HARTMUT SCHIROK
• Format: Patent
• Language: English; Japanese
• Published: 26.04.2018
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

PROBLEM TO BE SOLVED: To provide a new compound.SOLUTION: The present invention provides a compound represented by the following formula: ({2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-3-[tetrahydro-2H-pyran-2-yl]propanoyl}amino) benzoate (mixture of racemic diastereomers) or a salt of the compound, a solvate of the compound or a solvate of the salt of the compound.SELECTED DRAWING: None 【課題】新規化合物の提供。【解決手段】以下の式で表される化合物（｛２−［４−（５−クロロ−２−シアノフェニル）−５−メトキシ−２−オキソピリジン−１（２Ｈ）−イル］−３−［テトラヒドロ−２Ｈ−ピラン−２−イル］プロパノイル｝アミノ）安息香酸（ラセミ体ジアステレオマーの混合物）、または該化合物の塩、該化合物の溶媒和物もしくは該化合物の塩の溶媒和物の提供。【選択図】なし