1,1'-BIS(PHOSPHINO)FERROCENE LIGANDS FOR ALKOXYCARBONYLATION

• Main Authors: DIRK FRIDAG, NEUMANN HELFRIED, DONG KAI-WU, RALF JACKSTELL, DIETER HESS, KATRIN MARIE DYBALLA, FRANK GEILEN, ROBERT FRANKE, MATTHIAS BELLER
• Format: Patent
• Language: English; Japanese
• Published: 26.04.2018
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; THEIR RELEVANT APPARATUS; TRANSPORTING

PROBLEM TO BE SOLVED: To provide: novel ligands for alkoxycarbonylation, with which good yields of esters can be achieved; and a diastereomer mixture as a catalyst including the ligands.SOLUTION: The invention provides a diastereomer mixture of 1,1'-bis(phosphino) compounds each substituted by at least one heteroaryl group on the two phosphorus atoms, the mixture comprising two specific diastereomers, present in a specific molar ratio. For example, the invention provides a diastereomer mixture of 1.1'-bis(tert-butyl-2-pyridylphosphino)ferrocene. The invention further provides Pd complex mixture catalysts comprising the ligands.SELECTED DRAWING: None 【課題】エステルの良好な収率を達成し得るアルコキシカルボニル化のための新規なリガンド及び該リガンドを含む触媒としてのジアステレオマー混合物の提供。【解決手段】特定のモル比で存在する、２つのリン原子上で少なくとも１つのヘテロアリール基によりそれぞれ置換された１，１'−ビス（ホスフィノ）化合物のジアステレオマー混合物であって、２つの特定のジアステレオマーを有する。例えば、１．１'−ビス（ｔｅｒｔ−ブチル−２−ピリジルホスフィノ）フェロセンのジアステレオマー混合物。該リガンドを含有するＰｄ錯体混合物触媒。【選択図】なし