EXAMINATION KIT FOR FERRITIN DETECTION, AND FERRITIN DETECTING METHOD

• Main Authors: YUI KEI, OKUBO NORIO, YAMANAKA NOBUMITSU, ITO YUKIHIKO, KUSHIOKA TAKUYA, FUKUSHIMA MASAYUKI, BABA YUICHIRO, KATO SADAHIRO, OCHO MAKOTO
• Format: Patent
• Language: English; Japanese
• Published: 15.03.2018
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

PROBLEM TO BE SOLVED: To provide an examination kit for ferritin detection that shortens detection time of ferritin and improves detection sensitivity.SOLUTION: An immunochromatographic test kit for ferritin detection includes: an immunochromatographic planar test piece; and silica particles. The planar test piece is subjected to blocking treatment using a bovine serum albumin solution, and includes a test area and a reference area. In the test area, antibodies with a binding property to ferritin are stabilized. The silica particles having an average particle diameter of 30-400nm, are modified with the antibodies with the binding property to ferritin, and subjected to blocking treatment on a surface. Accordingly, detection time is shortened and detection sensitivity is improved in the test kit for ferritin detection.SELECTED DRAWING: None 【課題】フェリチンの検出時間の短縮と検出感度の向上を可能とするフェリチン検出用の検査キットの提供。【解決手段】イムノクロマトグラフィー用の平面試験片と、シリカ粒子とを具備する、フェリチン検出用のイムノクロマトグラフィー用試験キット。前記平面試験片はウシ血清アルブミン溶液を用いたブロッキング処理を施され、試験領域と参照領域とを有し、前記試験領域にはフェリチンとの結合性を有する抗体が固定化されており、前記シリカ粒子は平均粒径３０〜４００ｎｍであって、フェリチンとの結合性を有する抗体で修飾されるとともに表面にブロッキング処理が施されていることを特徴とする、検出時間が短縮し検出感度が向上したフェリチン検出用検査キット。【選択図】なし