TETRACYCLINE DERIVATIVES FOR TREATMENT OF BACTERIAL, VIRAL AND PARASITIC INFECTIONS

• Main Authors: ABATO PAUL, BHATIA BEENA, PAN JINGWEN, HONEYMAN LAURA, BERNIAC JOEL, KIM OAK K, GRIER MARK, ISMAIL MOHAMED, ASSEFA HAREGEWEIN, VERMA ATUL, NELSON MARK, BOWSER TODD
• Format: Patent
• Language: English; Japanese
• Published: 15.03.2018
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

PROBLEM TO BE SOLVED: To provide tetracycline derivatives for treatment of bacterial, viral and parasitic infections.SOLUTION: The present invention pertains, at least in part, to substituted tetracycline compounds of the formula (I), where X is CHC(RY'Y), CRR, C=CRR, S, NR, or O; E is NRR, OR,...