METHOD FOR PRODUCING RADIOACTIVE FLUORINE-LABELED ORGANIC COMPOUND

• Main Authors: NAKAMURA SOICHI, UMEHARA MEGUMI
• Format: Patent
• Language: English; Japanese
• Published: 11.01.2018
• Subjects: APPLICATIONS OF RADIATION FROM RADIOACTIVE SOURCES, NOTOTHERWISE PROVIDED FOR; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CONVERSION OF CHEMICAL ELEMENTS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; NUCLEAR ENGINEERING; NUCLEAR PHYSICS; OBTAINING ENERGY FROM RADIOACTIVE SOURCES; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; RADIOACTIVE SOURCES; THEIR RELEVANT APPARATUS; TRANSPORTING; UTILISING COSMIC RADIATION

PROBLEM TO BE SOLVED: To produce radioactive fluorine-labeled organic compounds using medical-use radioactive fluoride ions.SOLUTION: There is provided a method for producing a radioactive fluorine-labeled organic compound including: a process of, after first aqueous solution containing radioactive fluoride ions and sodium chloride is brought into contact with a carrier carrying silver ions, obtaining second aqueous solution containing radioactive fluoride ions separated from the carrier; and a process of synthesizing a radioactive fluorine-labeled organic compound by using radioactive fluoride ions contained in the second aqueous solution.SELECTED DRAWING: None 【課題】医療用の放射性フッ化物イオンを用いた放射性フッ素標識有機化合物の製造。【解決手段】放射性フッ化物イオンと塩化ナトリウムとを含む第１の水溶液を、銀イオンを担持する担体に接触させた後、前記担体から分離された、放射性フッ化物イオンを含む第２の水溶液を得る工程と、前記第２の水溶液に含まれる放射性フッ化物イオンを用いて放射性フッ素標識有機化合物を合成する工程と、を含む、放射性フッ素標識有機化合物の製造方法を提供する。【選択図】なし