TREATMENT OF ADRENAL INSUFFICIENCY

PROBLEM TO BE SOLVED: To provide improved pharmaceutical formulations of hydrocortisone and their use in the control of adrenal insufficiency in neonates, infants, small children, pre-pubescent children and the elderly.SOLUTION: There is provided a pharmaceutical composition adapted for oral adminis...

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Bibliographic Details
Main Authors MARTIN WHITAKER, HIEP HUATAN, RICHARD ROSS
Format Patent
LanguageEnglish
Japanese
Published 09.11.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide improved pharmaceutical formulations of hydrocortisone and their use in the control of adrenal insufficiency in neonates, infants, small children, pre-pubescent children and the elderly.SOLUTION: There is provided a pharmaceutical composition adapted for oral administration comprising: a micro-particulate carrier comprising an effective amount of hydrocortisone and a binding agent, and a taste masking polymer layer contacting the micro-particulate carrier.SELECTED DRAWING: Figure 1 【課題】ヒドロコルチゾンの改善された薬学的製剤、および新生児、乳児、小さい子ども、思春期前の子どもおよび高齢者の副腎機能障害の管理におけるその使用方法の提供。【解決手段】有効量のヒドロコルチゾンおよび結合剤を含むマイクロ微粒子担体と、該マイクロ微粒子担体と接している味覚マスキングポリマー層とを含有してなる、経口投与に最適化した薬学的組成物。【選択図】図１
Bibliography:Application Number: JP20170122497