2-ACYLAMINOPROPANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

• Main Authors: JOHN KANE, XIANG YIBIN, ANGELES DIOS, RICHARD SILVA, MIKAELA LEVINE, LISA M CUFF, JUNKAI LIAO, EDWARD LEE, CASSANDRA A CELATKA, SIEGEL CRAIG, BASTOS CECILIA M, DAVID J HARRIS, FREDERIC VINICK, THOMAS H JOZAFIAK
• Format: Patent
• Language: English; Japanese
• Published: 03.08.2017
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

PROBLEM TO BE SOLVED: To provide 2-acylaminopropanol-type glucosylceramide synthase inhibitors.SOLUTION: The present invention provides a pharmaceutical composition for treating polycystic kidney disease, comprising a compound represented by one of predetermined structural formulas or a pharmaceutically acceptable salt thereof.SELECTED DRAWING: None 【課題】２−アシルアミノプロパノール−タイプグルコシルセラミドシンターゼ抑制剤を提供すること。【解決手段】所定の構造式の１つによって表される化合物、またはその薬学的に許容可能な塩を含む、多発性嚢胞腎疾患の治療のための医薬組成物。【選択図】なし