BIXA ORELLANA COMPOSITION FOR TREATING MACULAR DEGENERATION

• Main Authors: VALERIE FONTAINE, JOSE-ALAIN SAHEL, STANISLAS VEILLET, RENE LAFONT
• Format: Patent
• Language: English; Japanese
• Published: 29.06.2017
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

PROBLEM TO BE SOLVED: To provide compounds and compositions for the treatment of macular degeneration.SOLUTION: A composition comprises Bixa orellana seed extract for photoprotection of mammalian retinal pigment epithelium. The composition is for applying to the treatment of mammalian age-related macular degeneration (AMD). The composition comprises a carrier in which the ingestion or injection into the eye or the injection into blood is acceptable. The composition further comprises ellagic acid and/or cyanidin. Furthermore, the composition is used in the treatment of Stargardt's disease and/or retinitis pigmentosa.SELECTED DRAWING: Figure 1 【課題】黄斑変性症治療のための化合物及び組成物の提供。【解決手段】哺乳類の網膜色素上皮の光保護のための、ビクサ・オレラナ種子抽出物を含む組成物。哺乳類の加齢黄斑変性症（ＡＭＤ）の治療に応用するための前記組成物。眼内への摂取或いは注射又は血液中への注射が許容される担体を含む、組成物。エラグ酸及び／又はシアニジンを更に含む前記組成物。更に、シュタルガルト病及び／又は網膜色素変性症の治療に、前記組成物を使用する方法。【選択図】図１